FDA announces new limits on high-dose simvastatin (Zocor)
The United States Food and Drug Administration (FDA) today announced new limitations to the use of high-dose simvastatin, due to the increased risk of muscle pain and weakness (myopathy) and in rare...
View ArticleEtanercept shows promise for treating dermatomyositis
A multicenter pilot study of etanercept for treatment of dermatomyositis found no major safety concerns and many patients treated with the drug were successfully weaned from steroid therapy. These...
View ArticleResearchers find new gene mutation associated with congenital myopathy
University of Michigan researchers have discovered a new cause of congenital myopathy: a mutation in a previously uncharacterized gene, according to research published this month in the American...
View ArticleNew research model to aid search for degenerative disease cures
(Medical Xpress)—Efforts to treat disorders like Lou Gehrig's disease, Paget's disease, inclusion body myopathy and dementia will receive a considerable boost from a new research model created by UC...
View ArticleVitamin D deficiency may contribute to alcohol-related muscular weakness
Myopathy refers to a muscular disease in which muscle fibers do not function, resulting in muscular weakness and wasting. Vitamin D deficiency is a well-recognized cause of myopathy, and excessive...
View ArticleUncleaned cells mean weak muscles
The protein complex mTORC1 promotes muscle growth. However, should this complex remain constantly active, it impairs the ability of the cells to self-clean, causing myopathy. Scientists working with...
View ArticleZebrafish help identify mutant gene in rare muscle disease
Zebrafish with very weak muscles helped scientists decode the elusive genetic mutation responsible for Native American myopathy, a rare, hereditary muscle disease that afflicts Native Americans in...
View ArticleResearchers discover link between expression of GATM and pain associated with...
(Medical Xpress)—A large team with members from several research institutions across the U.S. has found a possible link between the expression of the gene for glycine amidinotransferase (GATM) and pain...
View ArticleNew mechanism controlling proper organization of the muscle contractile units...
Muscle-specific protein cofilin-2 controls the length of actin filaments in muscle cells.
View ArticleUS patient is first outside Japan to receive new heart implant
George "Mac" McAllister had already endured two heart attacks, quadruple-bypass surgery, myopathy, ischemia of the heart and a congestive heart failure diagnosis by the time he arrived at the...
View ArticleScientists decode structure at root of muscular disease
Researchers at Rice University and Baylor College of Medicine have unlocked the structural details of a protein seen as key to treating a neuromuscular disease.
View ArticleGene discovery in debilitating muscle disorder
A coordinated research effort identified one of the genes involved in a debilitating muscle disorder.
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